1543
This number is a prime.
The German beer Köstritzer dates back to 1543. [Luhn]
The year of publication of three landmarks in science:
Andreas Vesalius published his De humani corporis fabrica
libri septem (Basel: Johannes Oporinus), Nicolaus Copernic
his De revolutionibus orbium celestium (Nuremberg: Johannes
Petreius), and Robert Recorde his Arithmetic or the ground
of Arts (London: Thomas Harper for John Harison). [Olry]
1543 and the 1543rd emirp (928607) contain the ten digits
once each. [Gaydos]
(There are 5 curios for this number that have not yet been approved by an editor.)
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